Most strikeouts in a Major League Baseball career
- WHO
- Lynn Nolan Ryan
- WHERE
- United States
- WHEN
- 1993
The Major League Baseball (MLB) record for most strikeouts in a career is 5,714 by Nolan Ryan (USA) playing for the New York Mets (USA), California Angels (USA), Houston Astros (USA), and Texas Rangers (USA) from 1966 to 1993.